Nutrition Updates
"LOSS OF BODY MASS LINKED TO DEVELOPMENT OF ALZHEIMER'S
DISEASE"
Loss of body mass over time appears to be
strongly linked to older adults' risk of developing Alzheimer's
disease (AD), and the greater the loss the greater the chance of
a person developing the disease, newresearch has found. The
findings are the first to associate decline in body mass index
(BMI) with the eventual onset of AD. The researchers suggest
that the loss of body mass reflects disease processes and
thatchange in BMI might be a clinical predictor of the
development of AD.
The research, reported in the September 27, 2005, issue of
"Neurology", was conducted by Aron S. Buchman, M.D., David A.
Bennett, M.D., and colleagues at Rush University Medical Center
in Chicago, IL, as part of
the Religious Orders Study. The Religious Orders Study is a
comprehensive, long-term look at aging and AD among Catholic
nuns, priests, and brothers nationwide that has been funded by
the National Institute on Aging (NIA), a component of the
National Institutes of Health, U.S. Department of Health and
Human Services, since 1993. Rush University Medical Center is
one of more than 30 Alzheimer's Disease Centers supported by the
NIA.
People who lost approximately one unit of
BMI per year had a 35 percent greater risk of developing AD
than that of people with no change in BMI over the course of the
study. Those with no change in BMI had a 20 percent greater risk
of developing the disease than that of people who gained
six-tenths of a unit of BMI per year."These
findings suggest that subtle, unexplained body mass and weight
loss in an older person may be an early sign of AD and can
precede thedevelopment of obvious memory problems,"
Alzheimer's Disease Education and Referral (ADEAR)Center
website at
http://www.alzheimers.org
Monday, September 26, 2005; 4:00 p.m. ET
CONTACT: Susan Farrer or Vicky Cahan, 301-496-1752,
301-785-3101(weekend cell)